Product Features: 
  • Authentic glycosylated homotrimer
  • Animal-component-free, protein-free production
  • Purity > 95%


Catalog No. Pack Size Price Quantity

1000 μg


100 μg


10 μg



Formulation Lyophilized from a 0.2 μm filtered solution of PBS
Molecular Weight 17 kDa, non-disulfidebonded homotrimer, glycosylated
Source Human Cell Expressed (HCE) in HEK-293 cells in the absence of animal-derived products
EC50 Typically ≤ 0.9 ng/ml
Purity > 95% (SDS-PAGE stained with Coomassie blue)
Endotoxin level < 1 EU/μg
Storage Lyophilized products are stable for one year at -20°C to -80°C from date of receipt. Upon reconstitution, the cytokine can be stored at 4°C for short term only (< 1 week), or at -20°C to -80°C in aliquots for long term. Avoid repeated freeze-thaw cycles. Refreezing should be performed on dry ice or in a dry ice/alcohol bath.

Tech Info / Data

11650 Purity Confirmation on SDS-PAGE

Recombinant human TNF-alpha, expressed in engineered human cells, belongs to the Tumor Necrosis Factor protein family. TNF-alpha is a non-disulfide linked homotrimeric glycoprotein. TNF-alpha is a proinflammatory cytokine produced in response to infection, tissue damage and inflammation by many immune cells such as monocytes and macrophages. TNF-alpha is an acute phase protein that initates production of other cytokines; it recruits neutrophils and macrophages at the site of infection by increasing the vascular permeability. TNF-alpha synergizes with other cytokines including IL-1 beta, IFN-gamma and TGF-beta. Genetic variations in TNF-alpha are correlated with autoimmune diseases.


Human TNF alpha Activity Assay

11650 Activity Assay

Related Products

Catalog No. Description Pack Size Price Quantity
11600-4 Human Serum Albumin, HCE  new 

1000 μg

11600-3 Human Serum Albumin, HCE  new 

100 μg


Find your product of interest by searching for category, species, molecule and/or application.

Visit our blog to read about recent developments in the fields of interferon, cytokine and biomarker research!

Sign up for our mailing list to be kept up-to-date on the latest promotions, company and product news.

Go to top