Human Oncostatin (OSM), Human Cell-Expressed (HCE)

Product Features: 
  • Authentic monomeric glyprotein
  • Animal-component-free, protein-free production
  • Purity > 95%

Ordering

Catalog No. Pack Size Price Quantity
11661-2

10 μg

$272.00
11661-3

100 μg

$1,496.00
11661-4

1000 μg

$4,847.00

Specifications

Formulation Lyophilized in PBS
Molecular Weight 30 kDa, monomer, glycosylated
Source Human Cell Expressed (HCE) in HEK-293 cells in the absence of animal-derived products
EC50 Typically 2 to 10 ng/ml
Purity > 95% (SDS-PAGE stained with Coomassie blue)
Endotoxin level < 1 EU/μg
Storage Lyophilized products are stable for one year at -20°C to -80°C from date of receipt. Upon reconstitution, the cytokine can be stored at 4°C for short term only (< 1 week), or at -20°C to -80°C in aliquots for long term. Avoid repeated freeze-thaw cycles. Refreezing should be performed on dry ice or in a dry ice/alcohol bath.

Tech Info / Data

11661 Purity Confirmation on SDS-PAGE
Background: 

Recombinant human Oncostatin M, expressed in engineered human cells, belongs to the IL-6-like protein family. OSM is a growth regulator for human fibroblasts and vascular smooth muscle cells. OSM induces the differentiation of megakaryocytes and is important in bone formation and wound healing. OSM synergizes antiproliferative effects with IFN-gamma and TGF-beta. OSM induces G-CSF and GM-CSF expression.

Citations

Human OSM Activity Assay

11661 Activity Assay

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