Human IL-6, Human Cell-Expressed (HCE)

Product Features: 
  • Authentic human glycosylation
  • High bioactivity and stability
  • Animal-component-free, protein-free production

Ordering

Catalog No. Pack Size Price Quantity
11605-2

10 μg

$208.00
11605-3

100 μg

$935.00
11605-4

1000 μg

$3,634.00

Specifications

Formulation Lyophilized from a 0.2 μm filtered solution of PBS
Molecular Weight 26 and 30 kDa, monomer, glycosylated
Source Human Cell Expressed (HCE) in HEK-293 cells in the absence of animal-derived products
EC50 Typically 0.2 to 1 ng/ml
Purity > 95% (SDS-PAGE stained with Coomassie blue)
Endotoxin level < 1 EU/μg
Storage Lyophilized products are stable for one year at -20°C to -80°C from date of receipt. Upon reconstitution, the cytokine can be stored at 4°C for short term only (< 1 week), or at -20°C to -80°C in aliquots for long term. Avoid repeated freeze-thaw cycles. Refreezing should be performed on dry ice or in a dry ice/alcohol bath.

Tech Info / Data

11605 Purity Confirmation on SDS-PAGE
Background: 

Recombinant human interleukin 6 (IL-6) is expressed by T-cells, endothelial cells, fibroblasts and other cell types. IL-6 expression can also be stimulated by a number of different factors including T cell mitogens, LPS, viruses and IL-1. IL-6 is a pleiotropic cytokine that regulates the development, proliferation and maturation of a number of hematopoietic cells and is essential for the maturation of B cells. It can also influence the growth and function of nerve cells, metabolism of bone and induction of acute phase proteins in hepatocytes.

Citations

Human IL-6 Activity Assay

11605 Activity Assay

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