Human IL-2, Human Cell-Expressed (HCE)

Product Features: 
  • Human interleukin 2 with authentic glycosylation
  • High bioactivity and stability
  • Animal-component-free, protein-free production

Ordering

Catalog No. Pack Size Price Quantity
11602-2

10 μg

$208.00
11602-3

100 μg

$604.00
11602-4

1000 μg

$2,393.00

Specifications

Formulation Lyophilized from a 0.2 micron filtered solution in PBS
Molecular Weight 15 kDa, monomer, glycosylated
Source Human Cell Expressed (HCE) in HEK-293 cells in the absence of animal-derived products
EC50 Typically 0.2 to 2 ng/ml
Purity > 95% (SDS-PAGE stained with Coomassie blue)
Endotoxin level < 1 EU/μg
Storage Lyophilized products are stable for one year at -20°C to -80°C from date of receipt. Upon reconstitution, the cytokine can be stored at 4°C for short term only (< 1 week), or at -20°C to -80°C in aliquots for long term. Avoid repeated freeze-thaw cycles. Refreezing should be performed on dry ice or in a dry ice/alcohol bath.

Tech Info / Data

11602 Purity Confirmation on SDS-PAGE
Background: 

Recombinant human interleukin 2 (IL-2), expressed in engineered human cells, is produced primarily by activated CD4+ T cells but is also expressed by naive CD8+ T cells, eosinophils, dendritic and thymic cells. IL-2 is an essential activator of the immune response and is required for the growth of T cells, activated B cells and T helper cell differentiation. IL-2 also stimulates the activity of NK cells and is involved in anti-inflammatory reactions and in hematopoiesis.

Citations

Human IL-2 Activity Assay

11602 Activity Assay

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