Human Erythropoietin (EPO), Human Cell-Expressed (HCE)

Product Features: 
  • Superior glycan profile over CHO expressed protein
  • Authentic human glycosylation
  • High bioactivity and stability

Ordering

Catalog No. Pack Size Price Quantity
11614-2

10 μg

$295.00
11614-3

100 μg

$1,099.00
11614-4

1000 μg

$4,847.00

Specifications

Formulation Lyophilized from a 0.2 μm filtered solution of PBS
Molecular Weight 36 kDa, monomer, glycosylated
Source Human Cell Expressed (HCE) in HEK-293 cells in the absence of animal-derived products
EC50 Typically 0.5 to 2.5 ng/ml
Purity > 95% (SDS-PAGE stained with Coomassie blue)
Endotoxin level < 1 EU/μg
Storage Lyophilized products are stable for one year at -20°C to -80°C from date of receipt. Upon reconstitution, the cytokine can be stored at 4°C for short term only (< 1 week), or at -20°C to -80°C in aliquots for long term. Avoid repeated freeze-thaw cycles. Refreezing should be performed on dry ice or in a dry ice/alcohol bath.

Tech Info / Data

11614 Purity Confirmation on SDS-PAGE
Background: 

Recombinant human erythropoietin, expresed in engineered human cells, belongs to the EPO/TPO protein family. EPO is an acidic hormone mainly produced by kidneys. EPO promotes erythroid progenitor cell differentiation and initiates hemoglobin synthesis. EPO acts by binding to a specific erythropoietin receptor (EPOR) present on the red blood cell precursor in the bone marrow, stimulating these cells to transform into mature erythrocytes. The EPO sensitivity progressively increases with differentiation of immature progenitor cells.

Citations

Human EPO Activity Assay

11614 Activity Assay

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